The passage of the American Recovery and Reinvestment Act (ARRA), which allocated billions of dollars to flow into health IT initiatives across the country, has ushered forth a new era for health IT. This is an unprecedented moment for healthcare stakeholders and government, at all levels, to invest significant resources toward health IT and health information exchange initiatives. This compendium, “Profiles of Progress 3: State Health IT Initiatives,” is a product of NASCIO’s Health IT Working Group. It provides a state-by-state “snapshot” of progress that each state has made toward developing and implementing health information exchange and other health IT initiatives. It specifically examines the role of the state CIO in these efforts, and also includes an overview of the implications for health IT since the passage of the ARRA.